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Process Engineer, MSAT

Company: Fate Therapeutics, Inc.
Location: San Diego
Posted on: December 6, 2019

Job Description:

Process Engineer, MSAT Job Code 308RA Description Fate Therapeutics is seeking an enthusiastic and skilled biochemical engineer to join our company s Manufacturing Science and Technology (MSAT) Team. The successful candidate will join a multidisciplinary team evaluating new technologies and developing novel processes for the scaled-up manufacturing of cellular immune therapies from human induced pluripotent stem cells (iPSC). The candidate will assist senior members of the MSAT team in the development of scaled-up culture, differentiation, purification and characterization methods for iPSC-derived cellular therapy products. Furthermore, they will actively support laboratory operations by coordinating the inventory, purchase and aliquoting of key reagents. This is a full-time position that will require dedicated weekend hours and is located at our corporate headquarters in San Diego, CA. Responsibilities Cell culture including the maintenance and expansion of feeder and iPSC lines Assist in the selection and evaluation of appropriate bioreactor platforms for the maintenance and expansion of feeder and iPSC lines Assist in the design and execution of experiments to develop new processes using bioreactors and new technologies Support the inventory and ordering of general laboratory reagents and materials, as well as aseptic preparation of reagent stocks, including media, cytokines and small molecules Timely and detailed record keeping of all activities Communicating experimental results to relevant team members and by presentations at MSAT team meetings Qualifications BS/MS in the Biological Sciences, Chemical or Biochemical Engineering or related field with 2 or more years of relevant experience Expertise with small- and large-scale mammalian cell culture Experience with 2D, wave and/or stirred-tank bioreactor platforms Experience with computation design of experiments and JMP software preferred Understanding of iPSCs, process development and/or immunology preferred Excellent record-keeping and communication skills Highly organized, possess a strong work ethic, and have the desire to acquire new technical skills in a fast-paced environment Working Conditions and Physical Requirements Will require working with cells and cell lines of human and/or animal origin Will require working with hazardous materials 100% on-site work at corporate headquarters in San Diego, CA Evening and weekend work (up to 8 hours on Saturday and Sunday with equivalent time off in the week) will be required The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and resume to: **************************** and reference Job Code 308RA About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for cancer and immune disorders. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company s immuno-oncology product candidates include natural killer (NK) cell and T-cell cancer immunotherapies, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens with chimeric antigen receptors (CARs). The Company s immuno-regulatory product candidates include ProTmune , a pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft-versus-host disease, and a myeloid-derived suppressor cell immunotherapy for promoting immune tolerance in patients with immune disorders. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit ************************.

Keywords: Fate Therapeutics, Inc., San Diego , Process Engineer, MSAT, Engineering , San Diego, California

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