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Research Associate, Protein Engineering

Company: Encodia, Inc.
Location: San Diego
Posted on: January 16, 2022

Job Description:

About Encodia:

Encodia is a rapidly growing platform company that is developing a new generation of protein analysis tools based on single-molecule protein sequencing. Our goal is to make protein sequencing easy and ubiquitous by using a novel reverse-translation technology that turns peptide sequences into DNA. The DNA can be read by a DNA sequencer, providing a path to breakthrough proteomics research at a scale that is not practical or cost-effective using current technologies.

Job Summary:

Encodia is seeking a highly motivated Research Associate with previous laboratory experience in protein engineering or protein biochemistry. The successful candidate will possess a BS or MS degree in Biochemistry, Molecular Biology, or related fields with an emphasis on protein structure and function. Previous experience with modern cloning techniques, library construction, high-throughput screening, and protein design is preferred.

Your Responsibilities:

  • Constructing high diversity mutant libraries, in addition to standard cloning vectors.
  • Screening protein variants using experiments such as phage, yeast, or mRNA display.
  • Preparing NGS samples and analyzing sequencing data.
  • Performing independent data analysis and communicating results.
  • Collaborating cross functionally to achieve other essential processes.
  • Maintaining a detailed lab notebook.


    What you bring to this role:
    • BS/MS in Biochemistry, Molecular Biology, or related fields with relevant work experience in industry or academic labs preferred.
    • Knowledgeable in general molecular biology laboratory procedures including PCR/qPCR, cloning, transformations, gel electrophoresis, etc.
    • Practical knowledge of basic microbiology and aseptic techniques.
    • Ability to accurately follow protocols, work efficiently, and generate data with high reproducibility and consistency.
    • Organized and detail-oriented with the ability to interpret, troubleshoot, and optimize experimental parameters.
    • Ability to work independently and cooperatively within a collaborative team environment.
    • Team player with excellent verbal and written communication skills.

      Highly Desirable:
      • Experience conducting in vitro binding assays
      • Familiarity with protein structure and molecular visualization software such as PyMol or similar
      • Working knowledge of Python or comparable programming language

        Encodia requires all on-site employees to be fully vaccinated for COVID-19 and to provide proof of vaccination at time of hire. This requirement extends to candidates for employment in order to participate in on-site interviews. Any candidate who is unable to meet the requirement may participate virtually in the interview process. As required by applicable law, the Company will consider requests for reasonable accommodations from this vaccine requirement where they do not cause Encodia undue hardship or pose a direct threat to the health and safety of others. Please let us know if you require a vaccination accommodation and a member of our Human Resources team will contact you.


        Encodia is an Equal Opportunity Employer. We offer a competitive and comprehensive employee benefits package including medical, dental, and vision, LTD, paid vacation, and a stock plan.

        We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Keywords: Encodia, Inc., San Diego , Research Associate, Protein Engineering, Engineering , San Diego, California

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