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Senior Data Engineer - Bioinformatics

Company: Guardant Health
Location: San Diego
Posted on: August 7, 2022

Job Description:

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has launched liquid biopsy-based Guardant360 -, Guardant360 CDx and GuardantOMNI - tests for advanced stage cancer patients. These tests fuel development of its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection.

Job Description

At Guardant Health we are applying cutting-edge methods in next-generation sequencing (NGS) to develop blood-based, non-invasive approaches to detect early stage cancers using a variety of genomic and epigenomic markers. We are seeking a Sr Data Engineer who will be responsible for designing, building, validating, and deploying Bioinformatics machine learning(ML) models and pipelines at scale, maintaining performance throughout the model lifecycle, and building tools to provide model explainability and transparency. Working knowledge of HPC environments as well as extensive AWS experience is required. Having a background in bioinformatics and genomics is highly desirable.


  • M.S in Bioinformatics, Computational Biology, Computer Science (PhD preferred)
  • Excellent programming skills(Python is a must) with 4+ years experience developing quality software; experience with the data science and ML is a plus
  • Experience with AWS services such as Data Lakes, Glue, Athena, Step Functions and SageMaker
  • Experience with high-performance computing environments (e.g. Slurm, SGE) and workflow execution tools (e.g. Nextflow, Snakemakel)
  • Experience in Continuous Integration / Delivery tools such as Jenkins and container tools such as Docker
  • Experience with Scaled Agile software development, Scrum and SDLC best practices
  • Experience working with a relational database, such as PostgreSQL
  • Bonus: Familiarity with next generation sequencing data analysis (DNA, RNA, or epigenetic analysis)
  • Great communication and presentation skills, ability to present clearly and ability to work cross-functionally

    Additional Information

    Covid Vaccination Policy: Starting January 7, 2022, Guardant Health will require all employees to be fully vaccinated to either (a) establish that they have been fully vaccinated against COVID-19; or (b) request and obtain an approved exemption from Guardant's COVID-19 U.S. Vaccination Policy as a reasonable accommodation, as consistent with applicable laws. An employee is considered fully vaccinated against COVID-19 two weeks after receiving the second dose of a two-dose vaccine or one dose of a single-dose vaccination. Acceptable vaccines are approved or under emergency use authorization by the U.S. Food and Drug Administration (FDA) and/or the World Health Organization (WHO). In addition, fully-vaccinated employees will be required to maintain their fully-vaccinated status under this policy by obtaining, if applicable, any FDA-approved boosters.

    Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

    Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

    All your information will be kept confidential according to EEO guidelines.

    To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

    Please visit our career page at:

Keywords: Guardant Health, San Diego , Senior Data Engineer - Bioinformatics, Engineering , San Diego, California

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