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Scientific Director (DMPK)

Company: NPAworldwide Recruitment Network
Location: San Diego
Posted on: October 19, 2020

Job Description:

JOB DESCRIPTION

Job #: 33064 Title: Scientific Director (DMPK) Job Location: San Diego, California - United States Employment Type: Salary: contact recruiter for details Other Compensation: 25% bonus Employer Will Recruit From: Nationwide Relocation Paid?: Yes WHY IS THIS A GREAT OPPORTUNITY? A global-leading pharma/healthcare products/medical products researcher and developer has an immediate need for a highly-skilled professional for their Scientific Director- Project Leader position dealing with Drug Metabolism and Pharmacokinetics (DMPK). This opportunity will be located in San Diego, CA. In this posoiton, you`ll have senior-level opportunity to direct and manage crucial DMPK R&D projects and processes focused on drug discovery and early development in all Therapeutic Area (TA) discovery teams. JOB DESCRIPTION

Responsibilities Include: Represent DMPK on multidisciplinary projects to provide scientific leadership and strategic direction Serve as the subject matter expert for DMPK during all stages of drug discovery and early development Play a critical role in the selection of lead compounds and nomination of development candidates, collaborating closely with Medicinal Chemistry, Biology, Toxicology, and Clinical Pharmacology Establish DMPK strategies that align with program goals and strive for high quality drug candidates Propose mechanistic approaches to understand the issues and drive drug discovery efforts Collaborate effectively with functional DMPK teams to ensure timely collection of critical data Prepare preclinical DMPK reports according to regulatory standards Initiate and facilitate collaborations with global DMPK, biology, modeling/simulation, and clinical pharmacology colleagues in support of PKPD Effectively communicate DMPK data and their relevance to project teams, management, regulatory authorities, and potential partners Participate in due diligence initiatives when required COVID-19 considerations:
There may be a mixture of virtual office and onsite activities for this position during the COVID-19 pandemic. If you do come into the office, you will see that all Company, CDC, and government regulations and restrictions are being strictly observed. QUALIFICATIONS Qualifications: Ph.D. in pharmacokinetics, drug metabolism, or related discipline with a minimum of 12 or more years of relevant industrial experience in the evaluation of small molecule therapeutics required. Experience with non-small modalities (e.g. peptides, oligonucleotides) desired. Broad understanding of DMPK concepts and relevant areas such as physicochemical properties, drug metabolizing enzyme & transporter kinetics, pharmacokinetics, mechanistic biotransformation and analytical sciences required. General understanding of PKPD concepts required. Ability to translate data into project relevance as part of anticipating and/or mitigating project challenges required. Ability to integrate data from multiple sources into a rational understanding of drug disposition required. Excellent negotiation and influencing skills, priority setting and adherence to project and departmental best practices and timelines required. Evidence of leadership in the DMPK field and a proven track record of scientific achievement & project influence, including ability to influence external scientific and regulatory practices through publication and other interactions required. Excellent verbal and written communication skills as well as strong interpersonal skills are essential required. This position will be based in San Diego and will require travel to other R&D sites up to 10-15% time. Education:
University - PhD

Keywords: NPAworldwide Recruitment Network, San Diego , Scientific Director (DMPK), Executive , San Diego, California

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