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Director, Chemical Biology

Company: Vertex Pharmaceuticals
Location: San Diego
Posted on: November 22, 2020

Job Description:

We're looking for a candidate to fill this position in an exciting company.

  • Integrate team activities with drug research projects and clearly articulate and communicate key questions that chemistry can help answer.
  • Develop knowledge of and make recommendations about future applications of chemistry to tackle new types of targets, such as DNA or RNA. --
  • Stay fluent with recent developments in the Chemical Biology field including advances in tagging proteins (preferably in live cells), biochemical and/or biophysical assay development and the rapidly evolving field of protein degradation.
    • ´╗┐Minimum Qualifications:
    • PhD in Chemistry or Biology and 10+ years of experience; 3-5 years' experience leading a small or mid-sized group preferably in an industrial setting
    • Demonstrated contributions in target and drug binding site identification and validation
    • Expertise in cell and molecular biology, biochemistry, and pharmacology and broad understanding of drug discovery
    • Expertise in biochemical and/or biophysical tools to evaluate small molecule drug binding to target protein
    • Experience in the application of genetic and/or computational methods to study pathways and identify targets
    • Expertise in chemistry, especially as it relates to probe design and/ or tissue targeting
    • Proven experience developing and mentoring group members
    • Effective communication skills, both verbal and written
    • Preferred Qualifications:
    • Experience in target and drug binding site validation and/or identification
    • Experience in planning, project leadership, laboratory and budget management
    • Shown ability to champion and advance creative concepts
    • Ability to manage complexity and ambiguity in a highly matrixed work environment
    • Ability to identify and lead collaborations in chemical biology field
    • A desire to be part of a highly innovative and dynamic company aimed at transforming the lives of people with serious diseases, their families and society´╗┐

Keywords: Vertex Pharmaceuticals, San Diego , Director, Chemical Biology, Executive , San Diego, California

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