Sr. Manager, Supply Chain (Drug Sourcing for Clinical Trials)
Location: San Diego
Posted on: May 15, 2022
Xencor is an innovative, clinical-stage biopharmaceutical
company located in the Los Angeles area-near Pasadena-and in San
Diego. We use our pioneering XmAb - technology to discover and
develop better biotherapeutics, antibodies and cytokines with
improved function, with the goal of improving patient outcomes and
quality of life. We have an excellent opportunity for a
Sr. Manager, Supply Chain (Drug Sourcing for Clinical Trials) to
join our team.
In this role you will be working remotely with the occasional in
office meeting - 1 day/week. We would prefer candidates who are
with in a commutable distance to San Diego
Our protein engineering capabilities and the modular nature of our
XmAb technology allow us to quickly identify and create new
platforms and drug candidates for potential development. We are
advancing a deep clinical pipeline of novel drug candidates,
including eight bispecific antibodies and two engineered cytokines,
and more programs are expected to start clinical testing in 2022.
We also leverage our many XmAb technologies by collaborating with
leading global biopharmaceutical companies, including Genentech and
Janssen Biotech, among others, and including our partnerships, 20
XmAb drug candidates are advancing through clinical development.
Three XmAb medicines, to treat patients with a range of serious
illnesses, such as aggressive lymphoma, rare blood disorders and
COVID-19, are now marketed worldwide by partners.
Our employees are the most important factor in our success, and we
have assembled a highly talented group from diverse backgrounds and
disciplines to execute our business plan and shape our future.
Xencor employees' value new ideas and flexibility and demand from
each other scientific rigor, a passion for innovation, and a
willingness to take risks.
Responsible for managing procurement and distribution activities in
support of Xencor clinical trials.
- Manages sourcing, procurement, and distribution of
biopharmaceutical clinical supply, comparators, and combination
drugs as required
- Ensures all clinical trials receive timely and adequate supply
for patients in support of the company's clinical studies
- Manages distribution activities in support of clinical
- Oversees all logistics issues related to shipments to
individual sites and to regional Depots as required
- Manages QP Release function, supporting QA in scheduling and
- Oversees Depots, providing input as to locations, operations,
and logistics in support of clinical trials
- Resolves shipping excursions on a timely basis in collaboration
- Ensures IP is cleared for import/export as required with
- Manages sourcing strategy and tactical activities for
comparator and combination drugs in support of Clinical
- Partners with CMC, QA, RA, and clinical operations to ensure
proper labeling strategy for comparator and combination drugs and
provide input and/or samples as needed
- Collaborates with CMC Drug Product and Supply Chain team
regarding required CMC budgeting, timelines and/or similar matters
to ensure a seamless flow of information and planning for the
clinical study to the CMC program level
- Develops effective supply strategies maximizing available
inventory by location and shelf life while minimizing waste and
- Leads risk mitigation through detailed insight of comparator
and combination drug supply and demand issues for programs of
strategic importance, cost, and/or constrained supply
- Assists in development of clinical supply budgets and revisions
- Adheres to all department and company-wide policies regarding
conduct, performance, and procedures
- Perform other duties as required
Position requires a Bachelor's degree, preferably in Life Sciences,
Business (Economics, Operations Management, Clinical Supply Chain
Management, Clinical Trials Coordination) or Engineering; Advanced
degree and APICS CPIM, CSCP certifications preferred. Also requires
at least 8 years of directly relevant work experience in clinical
supply chain management forecasting and planning for clinical
studies within Clinical Supply Chain, Clinical Operations,
Planning, Manufacturing, Quality, or other Supply Chain
disciplines, preferably in the Biotechnology/Pharmaceutical
industry. Also requires prior people and project management
experience for bulk drug products, IMP, comparators, and/or
The company reserves the right to consider internal experience in
lieu of the education or experience requirements listed above.
Position also requires:
- Strong knowledge of supply chain processes including internal
and external alignment (sourcing, manufacturing, quality,
analytics, regulatory, finance, clinical operations)
- Working knowledge of cGMP's as related to large molecule
biopharmaceutical activities, familiar with US, EU, and global
regulations applicable to investigational drugs and GCP regulations
applicable to investigational product and supply
- Flexibility and willingness to adapt to changing business
environment influences by developing and adopting new strategies
and tactics. Ability to think strategically and translate into
- Strong ability to collaborate and build strategic and tactical
relationships with internal (clinical operations, quality,
regulatory, etc.) as well as external (CDMO, CPO, storage sites,
- Strong budget management and financial analysis skills
- Ability to lead process improvement activities, delivering
business processes and/or technical solutions satisfying multiple
sets of stakeholders
- Strong planning, organization, and time-management skills to
juggle needs of multiple teams and projects simultaneously
- Ability to demonstrate good judgment in determining objectives
and approaches to assignments
- Excellent verbal/written communication and presentation skills,
including ability to simplify what is complex and focus audience on
- Strong computer (Excel, Word, PowerPoint, Visio) skills.
Experience with Clinical Demand Planning and Inventory management
systems. Physical, Mental and Environment Demands:
The physical, mental and working environment demands described are
representative of those that must be met by an employee to
successfully perform the primary functions of this position.
The physical demands when working in the office environment are
normally associated with extended amounts of time sitting and using
office equipment, including a computer, keyboard and mouse, which
can cause muscle strain. While performing the duties of this job,
the employee is frequently required to stand, walk and sit.
Periodic light lifting of supplies and materials may apply.
Specific mental demands for the position are listed above under
requirements. In addition, mental demands for this position
- Ability to multitask without loss of efficiency or accuracy,
including the ability to perform multiple duties from multiple
- Ability to work and sustain attention with distractions and/or
- Ability to interact appropriately with a variety of individuals
including vendors, customers and clients.
- Ability to maintain regular attendance and be punctual.
- Ability to understand, remember and follow verbal and written
instructions. Occasional travel may be required, including travel
between Xencor's Monrovia and San Diego offices. Additional travel
(domestic and/or international) for scientific conferences and/or
other meetings with collaborators is possible. Otherwise, work for
this position is generally performed at Xencor's worksite and
requires full-time commitment.
Xencor requires all employees to be fully vaccinated against
COVID-19 as a condition of employment. Being fully vaccinated means
that at least two weeks have passed since an individual's final
dose of an authorized COVID-19 vaccine regimen, including any
boosters recommended by the CDC. New employees will be required to
provide proof of their fully COVID-19 vaccinated status as of their
start date unless an exemption or accommodation is approved.
Americans with Disabilities Act (ADA) Statement
The Company will provide reasonable accommodations (such as a
qualified sign language interpreter or other personal assistance)
with the application process upon your request as required to
comply with applicable laws. If you have a disability and require
assistance in this application process, please contact .
To perform this job successfully, an individual must be able to
perform each essential duty satisfactorily. Reasonable
Accommodations may be made to enable qualified individuals with
disabilities to perform the essential functions.
Equal Employment Opportunity (EEO) Statement
The Company is an equal opportunity employer, and all qualified
applicants will receive consideration for employment without regard
to age, race, color, religion, sex, sexual orientation, gender or
gender identity, national origin, disability status, protected
veteran status or any other characteristic protected by state or
Xencor does not accept profiles or resumes from recruiting vendors
without a binding written agreement. Any unsolicited submission of
services and or resumes in no way creates an obligation or duty by
Xencor, implied or otherwise.
Keywords: Xencor, San Diego , Sr. Manager, Supply Chain (Drug Sourcing for Clinical Trials), Executive , San Diego, California
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