Director, Drug Metabolism and Pharmacokinetics (DMPK)
Company: Disability Solutions
Location: San Diego
Posted on: May 2, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
careers.bms.com/working-with-us .When you join BMS, you are joining
a diverse, high-achieving team united by a common mission. The
Pharmaceutical Candidate Optimization organization at Bristol Myers
Squibb is a dynamic, multi-disciplinary department that works to
discover and optimize new drug candidates. We work across all
therapeutic areas and all modalities (small molecules,
biotherapeutics, gene and cell therapies and other novel
modalities), and engage with all other R&D functions to advance
new assets in the BMS portfolio. Our integrated, cross-functional
teams apply deep expertise in drug metabolism, pharmacokinetics
(DMPK), toxicology, pharmaceutics, and bioanalysis to identify and
solve issues, discover high quality drug candidates, and enable
their clinical development.Here, you'll get the chance to grow and
thrive through opportunities that are uncommon in scale and scope.
You'll pursue innovative ideas while advancing professionally
alongside some of the brightest minds in biopharma.The Director,
Drug Metabolism and Pharmacokinetics (DMPK) for BMS-San Diego,
oversees the research activities of the San Diego based team of 9
scientists and will report to the global head of Discovery DMPK
within the Pharmaceutical Candidate Optimization (PCO) department.
They will interface with scientists focused on Discovery efforts in
San Diego and across BMS research sites. The PCO organization is a
multi-disciplinary department whose cross-functional teams apply
deep expertise in DMPK, toxicology, pharmaceutics and bioanalysis
to identify and solve issues, discover high quality drug candidates
and enable their clinical development. Key Responsibilities
Critical activities of this leader include proven ability to:
- Lead scientific efforts to characterize metabolic fate and
pharmacokinetic properties of drug candidates (small molecules,
biologics, and novel modalities) to inform and direct lead
optimization of drug candidates; proactively identify issues and
enable investigative efforts that further enhance optimization of
drug candidates
- Work collaboratively with the San Diego-based DMPK team and
internal partners to design, plan, execute and interpret DMPK
studies. The incumbent is expected to advise on strategies to
resolve DMPK issues that arise on programs.
- Work collaboratively with DMPK scientists across BMS discovery
sites to enable strategic integration of DMPK research across the
discovery portfolio
- Ensure that the DMPK team is current with emerging concepts and
technologies so that these tools can be applied as appropriate for
issues resolution.
- Work closely and collaboratively with colleagues in other
functions of PCO, including discovery toxicology, pharmaceutics and
analytical sciences to ensure a coordinated approach to discovery
efforts.
- Maintain a strong external presence in the DMPK community
through publications and conference presentations.
- Effectively lead, manage and develop DMPK scientistsBasic
Qualifications:Bachelor's Degree and 15+ years of Academic /
Industry experienceOrMaster's Degree and 12+ years of Academic /
Industry experienceOrPhD and 8+ years of Academic / Industry
experienceAnd6+ years of Leadership experiencePreferred
Qualification:
- Ph.D. degree in any area of drug disposition, with emphasis on
metabolism, pharmacokinetics or biochemical toxicology, with
experience in drug discovery and development. Knowledge of
computational approaches, including machine learning tools, to
advance predictive tools for ADME-related aspects of drug discovery
is desired.
- At least 8 years of experience in conducting and leading
research efforts in drug metabolism and pharmacokinetics
- At least 6+ years of leadership experience
- Proven track record of problem-solving skills and ability to
integrate across disciplines to address issues and identify
mitigation strategies.
- Highly effective written and oral communication skills
including contributions to the published literature.
- Strong interpersonal skills with evidence for effective
management of a dynamic team and commitment to professional
development of all personnel. For California Sites - The starting
compensation for this job is a range from $194,000 - $230,000, plus
incentive cash and stock opportunities (based on eligibility). The
starting pay takes into account characteristics of the job, such as
required skills and where the job is performed. Final, individual
compensation is decided based on demonstrated experience. For more
on benefits, please visit our BMS Careers site. Eligibility for
specific benefits listed in our careers site may vary based on the
job and location.If you come across a role that intrigues you but
doesn't perfectly line up with your resume, we encourage you to
apply anyway. You could be one step away from work that will
transform your life and career. Uniquely Interesting Work,
Life-changing CareersWith a single vision as inspiring as
Transforming patients' lives through science--- , every BMS
employee plays an integral role in work that goes far beyond
ordinary. Each of us is empowered to apply our individual talents
and unique perspectives in an inclusive culture, promoting
diversity in clinical trials, while our shared values of passion,
innovation, urgency, accountability, inclusion and integrity bring
out the highest potential of each of our colleagues.On-site
Protocol BMS has a diverse occupancy structure that determines
where an employee is required to conduct their work. This structure
includes site-essential, site-by-design, field-based and
remote-by-design jobs. The occupancy type that you are assigned is
determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned
facility. Site-by-design roles may be eligible for a hybrid work
model with at least 50% onsite at your assigned facility. For these
roles, onsite presence is considered an essential job function and
is critical to collaboration, innovation, productivity, and a
positive Company culture. For field-based and remote-by-design
roles the ability to physically travel to visit customers, patients
or business partners and to attend meetings on behalf of BMS as
directed is an essential job function. BMS is dedicated to ensuring
that people with disabilities can excel through a transparent
recruitment process, reasonable workplace
accommodations/adjustments and ongoing support in their roles.
Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/
eeo -accessibility to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your
area.Any data processed in connection with role applications will
be treated in accordance with applicable data privacy policies and
regulations.
Keywords: Disability Solutions, San Diego , Director, Drug Metabolism and Pharmacokinetics (DMPK), Executive , San Diego, California
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