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Associate Director/Director, Chemistry

Company: Boundless Bio
Location: San Diego
Posted on: November 11, 2019

Job Description:

Position Summary: As an Associate Director/Director, Chemistry at Boundless Bio, you will play a significant role in helping us transform exciting ecDNA discoveries into the next generation of cancer medicines. Using a range of chemistry techniques, primarily synthetic organic chemistry, structure-based drug design, and data analysis tools, you'll design and create new pharmaceutically active molecules to support the Boundless Bio drive for innovation. You will have management responsibilities and direct oversight of activities or CRO's and will be working closely within a multidisciplinary team to integrate biological, DMPK and formulation data to accelerate lead optimization to deliver clinical candidates. The AD/Director, Chemistry will also manage and support daily lab operation.
Duties and Responsibilities:Essential duties and responsibilities include the following. Other duties may be assigned.-- Responsible for the oversight, leadership, and implementation of Boundless Bio's drug discovery programs.-- Design novel small molecule drug candidates for in vitro/in vivo biological studies with the goal of providing proprietary clinical candidates. -- Manage 1-3 direct reports.-- Manage and oversees CRO activities and contractual relationship.-- Encourage collaboration with external partners and build strong external networks.-- Understand and incorporate pharmacological data in the design of novel small molecule drugs.-- Design synthetic routes to novel molecules which are robust, versatile and efficient.-- Carry out job responsibilities and assignments safely and maintain a clean and safe work area.-- Make and deliver presentations to management, scientific advisory board and consultants.-- Represents the company externally in scientific meetings and congresses.-- Demonstrated experience functioning within strong multi-disciplinary project teams.-- Perform all duties in keeping with Boundless Bio's core values, policies, and all applicable regulations.
Education/Experience
Minimum Requirements:-- Ph.D. or MS in Synthetic Organic or Medicinal Chemistry-- 5+ years of industrial experience in Drug Discovery & Development-- Demonstrated success working in a collaborative team environment.-- Strong written and interpersonal communication skills-- Management experience directing the activities of a chemistry team-- Ability to manage multiple projects in a fast-paced environment-- Ability to carry out investigations, performing experiments independently while obtaining accurate data and maintaining excellent laboratory records-- Ability to communicate effectively and work in team-based environment-- Ability to co-ordinate efforts with CROs as well as internal multi-disciplinary teams-- Experience working with legal functional group designing IP strategy as well as drafting and filing patents where the candidate is a lead or co-inventor-- Experience preparing and presenting data package to potential investors or potential clinical partners Desired:

  • Successful track record in a drug discovery environment, including advancing at least one program from hit to lead candidate.
  • Experience with structure-based drug design.

Keywords: Boundless Bio, San Diego , Associate Director/Director, Chemistry, Executive , San Diego, California

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