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Director, Gene Therapy Research

Company: Neurocrine Biosciences
Location: San Diego
Posted on: September 15, 2020

Job Description:

Who We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, distinctive and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve patient suffering and enhance lives.What We Do:Neurocrine Biosciences (Nasdaq: NBIX) is a neuroscience-focused, biopharmaceutical company with more than 25 years of experience discovering and developing life-changing treatments for people with serious, challenging and under-addressed neurological, endocrine and psychiatric disorders. Headquartered in San Diego, Neurocrine Biosciences specializes in targeting and interrupting disease-causing mechanisms involving the interconnected pathways of the nervous and endocrine systems.The company's diverse portfolio includes two FDA-approved treatments INGREZZA-- (valbenazine) for tardive dyskinesia and ORILISSA-- (elagolix) for endometriosis*, as well as clinical development programs in multiple therapeutic areas, including Parkinson's disease, chorea in Huntington disease, congenital adrenal hyperplasia, uterine fibroids* and polycystic ovary syndrome.* As part of a strategic collaboration with Voyager Therapeutics, Neurocrine Biosciences is also focused on the development of investigational gene therapy programs for the treatment of severe neurological diseases, including Parkinson's disease and Friedreich's ataxia. (*in collaboration with AbbVie)About the Role:The Director of Gene Therapy Research will be responsible for building a Gene Therapy Team to conduct all preclinical stage Gene Therapy programs at Neurocrine. Working with our Collaboration Partners and internal colleagues in Development, CMC, Clinical, Business Development, Legal, and Regulatory, the individual will participate in all stages of Gene Therapy drug discovery and development, including the management of existing programs, and the proposal and initiation of new projects. The individual will work cross-functionally with CMC and Development colleagues to efficiently progress early-stage Gene Therapy programs through to IND-enabling studies. The individual will also represent the Research Department on development teams and regularly interface with internal and external colleagues to ensure timely and accurate dissemination of data. They will also work with the Business Development team to monitor the latest developments in Gene Therapy Drug Development and assist in diligence activities on opportunities for potential partnerships._Your Contributions (include, but are not limited to):The primary role is to lead and manage the conduct of all Gene Therapy projects from inception to IND-enabling studiesWork with internal colleagues and external collaborators across all disciplines of R&D to select targets and develop Gene Therapy productsBuild a Research team to advance and grow Neurocrine's Gene Therapy franchiseIncrease Neurocrine's internal capabilities supporting current and future Gene Therapy opportunities.Monitor the latest developments in the Gene Therapy space for opportunities to in-license or acquire technologies that will keep Neurocrine's franchise current and competitiveRepresent Research on development-stage program teamsPrepare data summaries and present results to peers, colleagues and Neurocrine ManagementBe able to present data as appropriate at scientific meetings at the National and International level and help establish Neurocrine as a key contributor in the field.Be current with regulatory guidance for Gene Therapy productsOther tasks as assignedRequirements:PhD in Molecular Biology, Pharmacology, Neuroscience, or closely related discipline with at least 10 years of direct Gene Therapy Drug Development experienceStrong understanding of all aspects of Gene Therapy design and manufacturingExperience managing preclinical Contract Research OrganizationsExperience preparing INDs, CTAs, & BLAsProactive, innovative, with good problem-solving skillsExperience managing Research scientists/groups, including budgets and timelinesExperience and ability working within a cross functional team and matrix environmentExceptional verbal, presentation and written communication skills.Ability to travel up to 15%Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

Keywords: Neurocrine Biosciences, San Diego , Director, Gene Therapy Research, Healthcare , San Diego, California

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