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Senior Bioinformatics System Software Engineer

Company: Guardant Health
Location: San Diego
Posted on: November 22, 2020

Job Description:

Company_Description Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. Guardant Health Oncology Platform is designed to leverage its capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs. In pursuit of its goal to manage cancer across all stages of the disease, Guardant Health has launched multiple liquid biopsy- based tests, Guardant360 and GuardantOMNI , for advanced stage cancer patients, which fuel its LUNAR program, which aims to address the needs of early stage cancer patients with neoadjuvant and adjuvant treatment selection, cancer survivors with surveillance, asymptomatic individuals eligible for cancer screening and individuals at a higher risk for developing cancer with early detection. Since its launch in 2014, Guardant360 has been used by more than 7,000 oncologists, over 50 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers. Job_Description You will be part of the LUNAR bioinformatics team working on and with the software that is used in the clinical laboratory to process patient samples and analyze their genomic profiles, helping to prevent recurrence of cancer for cancer survivors based on a simple blood draw. Your role will be to work with Bioinformatics SQA engineers and members of the bioinformatics group to ensure the quality of bioinformatics software used in CLIA, CAP, NYDOH, and FDA regulated environments and the correct installation on production systems. Essential_Duties_And_Responsibilities * Work with bioinformatics SQA engineers and members of the bioinformatics group to develop test cases that ensure the quality of bioinformatics software used in CLIA, CAP, NYDOH, and FDA regulated environments. * Participate in requirements and design review meetings to create comprehensive, automated test strategies/plans for bioinformatics software leading to successful implementation and timely project completion. * Work with the algorithm development team to understand functional specifications, identify and design test cases for sequence analysis software including alignment, variant calling, and annotation software. * Work with cross-functional teams, and support integration and regression testing of Bioinformatics software. * Execute complex testing, perform in-depth statistical analysis, and interpret results independently. * Design, create, enhance, and maintain bioinformatics data simulators and automated testing framework to ensure excellent testing coverage. * Provide written documentation and specifications of software products and services. * Provide coaching to other team members for designing test strategies and test cases with strong knowledge of molecular biology, oncology and bioinformatics. * Report, track, and escalate anomalies discovered during testing (All testing phases) and ensure closure on issues. * Perform Impact Analysis for incremental changes and identify the scope of regression / test cycles and execute them as needed. Qualifications * Minimum with a BS Degree in Bioinformatics or related field * 4+ years of hands on experience with programming and scripting languages such as Python, R, C++, shell and RDBMS (SQL or Oracle) and software dev/ QA in Linux environment. * Strong understanding of sequencing data, annotations, and standard bioinformatics tools e.g. samtools, picard, snpEff. * 4+ years of hands on experience in scripting, running, analyzing, and refining automation frameworks for comprehensive and full application testing, including API testing. * 4+ years of experience in verifying algorithms, workflow or data analysis software. * Experience with test case management tools and best practices for scalability and maintainability. * 2+ years of experience in Continuous Integration / Delivery tools such as Jenkins and container runtime tools such as Docker * Excellent organization and people skills with the ability to work across functions to ensure successful integration testing. * Experience in testing bioinformatics software is preferred * Experience working in a regulated environment (CLIA, CAP, NYDOH, and FDA) preferred Additional Information Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Show moreShow less

Keywords: Guardant Health, San Diego , Senior Bioinformatics System Software Engineer, IT / Software / Systems , San Diego, California

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