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Scientist III (Cloner AND Binding)

Company: Aerotek
Location: San Diego
Posted on: May 23, 2020

Job Description:

Education/Experience (BMQ): B.Sc. in biophysics or biochemistry and at least 7 years of relevant experience or PhD with no experience. Deep understanding of ligand binding kinetics and thermodynamics, including supporting equations and assumptions. Experience performing, analyzing, and designing routine, innovative, and troubleshooting experiments for quantitative biochemical and /or biophysical assays is required. Experience working in a molecular biology lab executing routine cloning, DNA sequence analysis and protein extraction projects is required. Additional preferences: Experience working with direct binding methods, including at least one of the following: MST, DSF, SPR, or ITC, is a plus. Essential Duties and Responsibilities: Independent strategic design and execution of novel (company product) assays for diverse targets and target classes. Includes independent experimental design, troubleshooting, and data analysis in Excel and Graphpad. Work closely with the Screening Operations team to execute development experiments and commercial implementation. Lead and execute ad hoc cloning projects using Gateway and/or restriction-based cloning, routine sequence verification for large clone arrays, protein extraction and Western blot analysis Develop new assays using microscale themophoresis to measure direct ligand binding across various protein classes. Key point scientist leading large client projects; includes routine client meetings and presentations, updates, and execution of client goals. Support the Business unit by contributing to scientific meetings and publications and provide internal marketing material. Routine and ad hoc mentorship of junior and senior R&D and operations colleagues. Identity areas where software would greatly improve operation efficiency and write user requirements for the development of software tools (no coding required). With minimal supervision, design and execute troubleshooting experiments to improve TAT. Develop and optimize SOPs as part of continuous improvement program, perform routine QC on equipment and new reagent lots, maintain inventory of key reagents. Be conscientious and active learner Good record keeping in lab notebook following SOP to the letter Demonstrates and promotes the company vision Regular attendance and punctuality Applies GMP/GLP in all areas of responsibility, as appropriate Conducts all activities in a safe and efficient manner Performs other duties as assigned Owns the accountability and responsibility of delivering to client needs and timeliness Provides cross-functional support to other departments as required Adjusts work hours as needed to meet client deadlines Adheres to site employee health and safety (EHS) requirements About Aerotek: We know that a company's success starts with its employees. We also know that an individual's success starts with the right career opportunity. As a Best of Staffing -- Client and Talent leader, Aerotek's people-focused approach yields competitive advantage for our clients and rewarding careers for our contract employees. Since 1983, Aerotek has grown to become a leader in recruiting and staffing services. With more than 250 non-franchised offices, Aerotek's 8,000 internal employees serve more than 300,000 contract employees and 18,000 clients every year. Aerotek is an Allegis Group company, the global leader in talent solutions. Learn more at Aerotek.com.

Keywords: Aerotek, San Diego , Scientist III (Cloner AND Binding), Other , San Diego, California

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