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Senior Scientist I

Company: Biological Dynamics, Inc.
Location: San Diego
Posted on: September 16, 2020

Job Description:

Based in San Diego, CA, Biological Dynamics, Inc. (BioDyn) is a privately held molecular diagnostics Company committed to improving global cancer outcomes by empowering healthcare communities with low-cost, accessible cancer diagnostics for labs and point-of-care. At BioDyn, we are developing a suite of novel oncology tests for early cancer detection, treatment response, and recurrence monitoring. The company’s lab-on-a-chip platform offers a novel way to isolate cell-free nanoparticles and macromolecules directly from whole blood, serum, or plasma. In addition to lab-focused products, the Company is also developing a smartphone-enabled portable version of the platform, extending molecular testing into homes. Our diverse team shares passion for improving patient care, a focus on cutting-edge technology, and a deep commitment to innovation, which shapes the future of our Company and drives our innovative culture.

Job Summary

The individual in this position will work within the Assay Development department to develop protein- and exosome-based assays on our proprietary detection technology platform, Verita™, AC Electrokinetics/Lab on a Chip (ACE/LOC). The candidate must be familiar with new product development phases—establishing technical feasibility of an assay, development, transfer, verification, and validation. The candidate must be able to efficiently design and execute experiments, perform data analysis, and communicate results and observations effectively both as presentations and QMS-compliant documentation. This is a hands-on role, requiring an individual capable of designing and developing new assays utilizing our proprietary detection technology. The ideal candidate must be goal-oriented and must thrive in an entrepreneurial environment which necessitates a hands-on approach at all levels.

Is comfortable and effective at working with un-optimized platforms and driving them to repeatably meet performance specifications by developing proper calibrators and controls

Determines approaches for endeavors that align with the company’s product development goals, with an emphasis on protein biomarker detection and development of robust assays

Independently designs and performs experiments for R&D activities while providing insight and recommendations for achieving short and long-term goals

Discovers and effectively communicates insights into the fundamentals of the interaction between the ACE/LOC technology and the biological variables that allow for a detection and quantification of biomarkers.

Serves as mentor and project lead for other scientists, engineers and research associates in areas of expertise as needed

Partners effectively with other members of the R&D team, as well as Engineering, Quality, Marketing, and all other departments in support of Product Development objectives

Effectively communicates experimental findings in written and verbal formats during internal and external meetings

Develops new analysis approaches for experimental data and discovers connections between unrelated variables

Other responsibilities/projects as assigned.

Education/Experience/Skills

Ph.D. in Biochemistry, Bioengineering, Molecular Biology or a closely related field and 3+ years applicable industry work experience

Expertise in biochemical assay design, construction and rollout to manufacturing; molecular assay and/or immunoassay experience in the same

Experience in oncology, with a focus on protein analysis

Expertise in formulation of biocompatible buffers

Expertise with statistical data analysis and knowledge of statistical software such as GraphPad Prism or JMP is a plus

Detail- and goal-oriented, with the ability to exercise independent judgment to determine methods and procedures on new assignments

Skilled at writing QMS-compliant plans, reports, and SOPs

Effective at planning, organizing, and prioritizing

Strong troubleshooting and problem-solving skills

Able to handle pressure and ambiguity and maintain composure and focus in situations of uncertainty

Demonstrated sense of urgency to deliver high quality results under tight timelines

Adept at building strong relationships and collaborating with colleagues at all levels

Effective communication skills, both verbal and written

Do you have a Ph.D. in Biochemistry, Bioengineering, Molecular Biology or a closely related field? * Do you have at minimal one year experience, excluding post-doc, within a private or public for-profit company? *

Describe your assay and/or immunoassay experience *

Your full LinkedIn profile

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Keywords: Biological Dynamics, Inc., San Diego , Senior Scientist I, Other , San Diego, California

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