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Scientist/ Senior Scientist, Molecular Biology and Protein Sciences Group

Company: AlivaMab Discovery Services
Location: San Diego
Posted on: February 23, 2021

Job Description:

US-CA-San DiegoID: 2021-1396Category: Research & DevelopmentOverview

Overview:

AlivaMab Discovery Services ("ADS") seeks an outstanding individual with exceptional molecular biology skills for the position of Scientist/Sr. Scientist in the Molecular Biology and Protein Sciences group. The successful applicant will have responsibility for managing molecular biology activities in the Molecular Biology and Protein Science group. This position offers the opportunity for substantial career growth and the ability to help discover the medicines of tomorrow. The candidate will report to the Associate Director of Molecular Biology and Protein Science and work closely with scientists and leaders in the Antibody Discovery Group.

ADS combines deep expertise and innovative technologies for the rapid discovery and development of superior antibody therapeutics. The company has developed a highly optimized fully-integrated antibody therapeutic discovery and development platform that leverages the AlivaMab Mouse technology and the ADS team's expertise to deliver diverse panels of highly characterized fully human antibody leads in unparalleled timelines. We seek talented, experienced, and enthusiastic people to join our team as we build a premier organization to meet and exceed the expectations of partners conducting antibody therapeutic discovery and development. The successful applicant will be a key contributor in a fast-growing team dedicated to delivering superior therapeutic antibody candidates that will improve outcomes for patients.

Responsibilities

Key Responsibilities:

  • Initial primary responsibilities will be molecular recovery of antibody sequences, antibody sequence analysis and assessment either utilizing Sanger sequencing or NGS methods and workflows associated with each
  • Vector construction for antibody expression and immunization campaigns, and associated workflows associated with each
  • Independently plan and execute experiments, analyze results, and present data at team meetings
  • Generate, organize, and maintain meticulous records all conducted experiments

    Qualifications

    Qualifications:
    • Ph.D. with a minimum of 2 years of antibody related experience in a biotechnology or pharma company or a BS/MS with a minimum of 7 years of related experience
    • Experience with molecular biology techniques (PCR, DNA/RNA isolation, plasmid prep, gel extraction, cloning, Sanger sequence analysis)
      • Candidate will have NGS experience include adapter ligation, library validation, and NGS data analysis
      • Experience working with mammalian cell culture
      • Antibody engineering, expression, and purification is a plus
      • Excellent trouble shooting and problem-solving capabilities
      • Extraordinary attention to detail, planning, and organizational skills and can manage multiple projects simultaneously
      • History of timeline-driven delivery
      • Outstanding presentation and communication skills

        The successful applicant should be prepared to work in a high-energy, goal- and timeline-driven environment. Good internal and external collaborative abilities are required, including excellent listening and creative problem solving. The successful applicant will be high functioning in an environment dedicated to exceptional quality and integrity. Excellent communication skills and being able to present in front of internal and external audiences is required. Proficiency in Microsoft Office, Snap Gene, and any other programs necessary for the position are required.

        AlivaMab Discovery Services is a privately held technology company with an integrated therapeutic antibody discovery platform that combines innovative technologies and deep expertise to deliver superior antibody drug candidates in rapid timelines. The combined experience of the team is demonstrated by their proven track record of having executed over 200 discovery projects yielding multiple antibody drug candidates that have entered clinical trials. ADS delivers diverse panels of high affinity antibody therapeutic candidates with extensive molecular and epitope diversities, functional and kinetic characterization and superior developability profiles. The integrated platform spans from the collaborative process of designing the discovery plan to the delivery of fully human therapeutic antibodies. ADS is trusted by partners ranging from global pharmaceutical companies to virtual biotechnology organizations.

        AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

        PM18

        #LI-DNI PI130718484

Keywords: AlivaMab Discovery Services, San Diego , Scientist/ Senior Scientist, Molecular Biology and Protein Sciences Group, Other , San Diego, California

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