Principal Associate

Company: Emergent BioSolutions Inc
Location: San Diego
Posted on: February 23, 2021

Job Description:

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Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and growth opportunities. Here, you will join passionate professionals who advance their scientific, technical and professional skills to develop products designed-to protect life. Position Summary The position will report to the Sr. Scientist of the Product Development (PD) department in San Diego. This position will be focused on the support of analytical assay work to screen stable vaccine formulation and develop formulation process to manufacture vaccine drug product in liquid or powder dosage form. Essential Functions Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions.

• Provide Liquid and Powder formulation analytical support
• Participate in development work and provide analytical support for the vaccine formulation development and fill-finish process. Key example includes but not limited to ELISA, PCR, TCID50, UV-Vis, HPLC
• Develop and optimize lyophilization cycles that are well-documented and easily scaled-up
• Pharmacy manual preparation for clinical studies
• Organize development stability study and perform the sample management
• Use professional concepts, company policies, and procedures (SOPs) to complete routine assignments by performing scientific functions in collaboration with others.
• Make detailed observations, consistently analyze data and interpret results to make scientifically valid conclusions
• Review data obtained for compliance to specifications and reports abnormalities
• Write and revises standard operating procedures (SOP), development protocols and other related documentation.
• Troubleshoot and optimize development protocols when necessary
• Document laboratory work consistent with company requirements
• Maintain a clean and sanitary work area in accordance with standard laboratory practice and safety procedures
• Work productively with other team members as well as on independent assignments
• Train and provide assistance to junior staff Minimum Education, Experience and Skills
  • 4-6 years of experience in the biopharmaceutical industry and knowledge of oral solid dosage form and liquid dosage forms.
  • A minimum of a bachelor's degree. BS degree in chemistry, biochemistry, molecular biology, pharmaceutical development or a related field is preferred.
  • Understanding of protein/biomolecule's biophysical properties and characterization
  • Experience with protein/formulation characterization assay such as including DLS, pH, Osmolality, Moisture content, Disintegration, UV-Vis, Intrinsic Fluorescence measurement, HPLC
  • Experienced with aseptic techniques, maintenance of mammalian cell lines and cell-based assay
  • Design, execute and interpret experiments with a high degree of reliability and independence is preferred
  • High capability of multitasking and handling multiple projects at the same time in a fast-paced environment
  • Excellent written and verbal communication skills required
  • Good aseptic techniques
  • Ability to effectively collaborate with team members
  • Strong trouble shooting and data analysis skills
  • Handling experience of Virus like particle (VLP), live attenuated virus and Bacterial formulation is a plus
  • Experience with lyophilization development is recommended but not required
  • Knowledge of Design of Experiment (DoE) and statistical analysis tools is a plus There are physical/mental demands and work environment characteristics that must be met by an individual to successfully perform the essential functions of the job. This information is available upon request from the candidate.-- Reasonable accommodations may be made to enable individuals with disabilities to perform all essential functions.
    -- Emergent BioSolutions is an Equal Opportunity/Affirmative Action Employer and values the diversity of our workforce. Emergent does not discriminate on the basis of race, color, creed, religion, sex or gender (including pregnancy, childbirth, and related medical conditions), gender identity or gender expression (including transgender status), sexual orientation, age, national origin, ancestry, citizenship status, marital status, physical or mental disability, military service or veteran status, genetic information or any other characteristics protected by applicable federal, state or local law.
    -- Information submitted will be used by Emergent BioSolutions for activities related to your prospective employment. Emergent BioSolutions respects your privacy and any use of the information submitted will be subject to the terms of our Privacy Policy .
    -- Emergent BioSolutions does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on Emergent BioSolutions' approved agency list. Unsolicited resumes or candidate information submitted to Emergent BioSolutions by search/recruiting agencies not already on Emergent BioSolutions' approved agency list shall become the property of Emergent BioSolutions and if the candidate is subsequently hired by Emergent BioSolutions, Emergent BioSolutions shall not owe any fee to the submitting agency. ABOUT EMERGENT Protecting and Enhancing 1 billion lives by 2030 focuses our energy to improve the quality of life for individuals around the world, giving them the opportunity to experience the fullness of life. Our drive towards this vision informs all of our actions-whether it is our approach to product development, manufacturing, encouraging employee health and wellness or giving back to the community-we strive every day to achieve this shared goal. WE BELIEVE IN OUR VALUES
    • Stand shoulder to shoulder no matter what
      • We combine our best thinking and communicate openly to support each other.
      • Break through thinking
        • We take smart risks, pursue innovation and challenge ourselves to constantly improve.
        • Own it always
          • Every person at Emergent is engaged and accountable for delivering on our commitments.
          • Compete where it counts
            • We set the right goals and respect each other as we conquer them together.

Keywords: Emergent BioSolutions Inc, San Diego , Principal Associate, Other , San Diego, California