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Senior Scientist in Biochemical Toxicology

Company: Kelly Services
Location: San Diego
Posted on: September 24, 2022

Job Description:

Senior Scientist in Biochemical Toxicology Kelly Outsourcing & Consulting Group (KellyOCG), a managed solution provider and business unit of Kelly Services, Inc., is currently seeking a Senior Scientist in Biochemical Toxicology for a long-term engagement at one of our Global clients in San Diego, CA. This role is a full-time, fully benefitted position. As a KellyOCG employee you will be eligible for Medical, Dental, 401K and a variety of other benefits to choose from. You'll also be eligible for paid time off, including holiday, vacation, and sick/personal time. All KellyOCG employees receive annual performance reviews. Senior Scientist in Biochemical Toxicology to be located in La Jolla, CA. Scope and responsibilities

  • Develop and implement translational safety strategies to support project teams to develop lead molecules, for multiple drug modalities such as siRNA, PROTAC,
  • Bispecific antibody, CAR T-cell therapy and so on
  • Leverage multi-omics datasets by collaborating with bioinformaticians
  • Initiate and perform early hypothesis-driven investigation into mechanisms of various tissue or organ toxicities for the proactive management of potential safety liabilities and communication of impact to teams
  • Work closely and be an avid contributor within the multi-disciplinary team to leverage expertise in immunology, cell molecular biology, computational chemistry and biology
  • Be part of the evidence generation group by working closely with pathologists, toxicologists, DMPK scientists, chemists and others to aid submission and mitigate toxicology findings
  • Communicate study results and provide guidance to stakeholders in applying those results toward strategic decisions
  • Identify, pilot, and evaluate emerging novel technologies to expand translational capabilities
  • Help build external network of leaders to enable strategic partnerships in translational and biomarker research Qualifications: Required Skills:
    • PhD in biochemistry or a related field with at least 5 years, or MS with at least 10 years, of post-graduate experience in an academic or industry setting.
    • An extensive background in proteomics and/or mass spectrometry imaging is required.
    • A track record of de novo mass spectrometry methodology design for both small and large molecules in complex biological samples is required.
    • Proven record of creative thinking and a deep understanding of biology is required
    • Excellent analytical, communication and collaboration skills are required.
    • Experience with biochemical, molecular and cellular biology techniques. Fluorescence imaging is required. Preferred Skills:
      • Demonstrated project team experience at a pharmaceutical company and ability to work effectively in a matrix, global environment as part of a multidisciplinary team is strongly preferred.
      • Ability to leverage large omics data sets preferred.
      • First-hand experience with cell cultures e.g., organoid iPSC preferred.
      • Clinical biomarker experiences preferred.
      • Strong self-motivation and drive to make impactful contributions is crucial. #P1

Keywords: Kelly Services, San Diego , Senior Scientist in Biochemical Toxicology, Other , San Diego, California

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