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Senior Scientist, Translational PK/PD

Company: Disability Solutions
Location: San Diego
Posted on: September 21, 2023

Job Description:

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Translational PK/PD to be located in San Diego, CA, Spring House, PA or Beerse, Belgium. At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies. The Senior Scientist modeling approaches used may include physiologically based pharmacokinetic modeling, mechanistic PK/PD modeling, and/or systems pharmacology modeling to help (a) predict preclinical and clinical PK profiles (b) quantify exposure/ response relationships for target engagement biomarkers, efficacy, and potential adverse effects, and (c) guide in vivo and in vitro experimental designs that will be most informative for modeling. Key Responsibilities:

  • Apply Pharmacokinetic/Pharmacodynamic (PK/PD) modeling to drive project team decisions from early discovery through early clinical studies.
  • Contribute to guiding modeling and simulation strategies within the organization.
  • Act as a key member of discovery project teams and interact closely with biology, chemistry, and other drug metabolism and pharmacokinetic (DMPK) project members to help craft the most appropriate preclinical and early clinical studies and the associated quantitative model-based analyses to advise candidate selection and dosing recommendations.

Keywords: Disability Solutions, San Diego , Senior Scientist, Translational PK/PD, Other , San Diego, California

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