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Scientist, Chemical Development

Company: Neurocrine Biosciences
Location: San Diego
Posted on: November 18, 2023

Job Description:

Scientist, Chemical Development page is loaded Scientist, Chemical Development Apply remote type On-Site locations US CA San Diego time type Full time posted on Posted 2 Days Ago job requisition id R4149 Who We Are: At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options. What We Do:Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVieAbout the Role:Responsible for independently carrying out research and tasks necessary to develop chemical processes and support scale up and manufacturing of drug substances. _ Your Contributions (include, but are not limited to):

  • May provide engineering support to the chemical development department
    • Independently designs, plans and executes activities towards the goals of one or more Chemical Development projects to support preclinical through commercial activities
      • Evaluates, develops and implements synthetic changes on Chemical Development projects
        • Independently performs process R&D and optimization of synthetic routes, including experimentation for compound preparation, synthetic route scouting, process development and process trouble-shooting
          • Supports kilo-lab operations including equipment configuration, maintenance, and operation
            • Procures, installs and maintains common-use chemical development instrumentation
              • Effectively documents research and development work
                • Provides support for off-site synthesis, manufacturing activities and interaction with contractors
                  • Promotes and ensures a safe environment for operations performed in the laboratory
                    • Provides training and/or supervision to junior staff, as needed
                      • Other duties as assignedRequirements:
                        • BS/BA degree in chemistry, chemical engineering, or similar scientific discipline and 2+ years of experience in experience in pharmaceutical/process development field, including API manufacturing experience OR
                        • MS/MA degree in chemistry, chemical engineering or similar scientific discipline and some industry experience preferred OR
                        • PhD in chemistry, chemical engineering or similar scientific discipline andsome relevant experience preferred
                        • Good knowledge of scientific principles, methods and techniques
                        • Strong computer skills
                        • Good communications, problem-solving, analytical thinking skills
                        • Detail oriented
                        • Ability to meet deadlines
                        • Good project management and interpersonal skills
                        • Ability to creatively solve complex problems in a team environment
                        • Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
                        • Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
                        • Effective report writing, and oral presentations skills
                        • Must be able to build excellent working relationships & maintain confidentiality regarding intellectual property and proprietary endeavors of the company
                        • A thorough understanding of organic and process chemistry, as well as familiarity with current literature and the ability to search the literature
                        • Understanding manufacturing and cGMP requirements in Chemical Development is a plus
                        • Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
                        • Ensures laboratory work is done productively and practices safe laboratory skills
                        • Performs process R&D and optimizes synthetic routes
                        • May provide input for portion(s) of CMC regulatory documentation and supporting work
                        • Drug substance process development, scale up, and manufacturing experience is a plus
                        • Mechanical inclination is a plus#LI-AD1 Neurocrine Biosciences is an EEO/AA/Disability/Vets employer. We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description. _ The annual base salary we reasonably expect to pay is $84,100.00-$122,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. About Us OUR VALUES:
                          • PASSION: We are driven and love what we do. We are committed to our goals and to making a difference.
                          • INTEGRITY:We do the right thing for patients and our community. We take accountability. We speak up.
                          • COLLABORATION: We trust one another. We are inclusive. We are respectful. We are transparent. Together we succeed.
                          • INNOVATION: We seek and create optimal solutions.
                          • TENACITY:We do not quit. We adapt. We accomplish what others cannot. Come join our team during this exciting time of growth and opportunities! We are a top place to work. Neurocrine Biosciences was named one of the FORTUNE Best Workplaces in Biopharma--- 2023. We were also named a Great Place to Work - Certified company and were recognized on Great Place to Work's Best Workplaces for Parents--- 2020 list. -2023 Fortune Media IP Limited. All rights reserved. Used under license.

Keywords: Neurocrine Biosciences, San Diego , Scientist, Chemical Development, Other , San Diego, California

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