Scientist I, GI Inflammation Discovery Research

Company: Takeda
Location: San Diego
Posted on: November 20, 2023

Job Description:

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Scientist I where you will independently design and execute target engagement (TE) and pharmacodynamic (PD) biomarker assays from preclinical models. You will also identify and implement new assay technologies that have an impact on project advancement, assay throughput and/or assay performance. As part of the, Inflammatory Disease Research team you will report to the Senior Director and Head Celiac Discovery and work closely with preclinical pharmacology, DMPK and clinical biomarker and translational groups to develop integrated biomarker plans.

How you will contribute:

• Independently designs and validates well-defined and controlled experimental procedures to measure pharmacodynamic, target engagement, and disease specific biomarkers in preclinical models and in human samples.
  
• Exercises technical judgement in execution of studies and interpretation of complex results, initiates routine and non-routine problem investigation and recommends solutions.
  
• Performs calculations and basic analysis on experimental results and develops hypotheses.
  
• Utilizes a battery of in vitro assay technologies execute on pipeline programs including (but not limited to): MSD, ELISA, qPCR, flow cytometry.
  
• Maintains responsibility for routine laboratory instrumentation and supplies, and maintains good records.
  
• Prepares detailed protocols / SOPs that enable transfer of validated assays to project team members and collaborators.
  
• Prepares and presents endpoint analysis to project teams.
  
• Expected to organize time and plan specifics of project related work with oversight from manager.
  
• 100% lab based at San Diego site.
  
  
  Minimum Requirements/Qualifications:
  
  
  • BS with 8+ years research experience, or MS with 6+ years research or PhD (no post doc required).
    
  • Experience; in a scientific discipline of cellular & molecular biology, immunology, or equivalent.
    
  • Demonstrates significant knowledge of basic immunology, assay development and biomarkers.
    
  • Communicates and collaborates with colleagues effectively.
    
  • Knowledge in the use of common analytic software's including Microsoft Office programs and Graphpad Prism.
    
  • With latitude in specific areas, plans and executes experiments with appropriate controls; decisions have moderate to advanced scope and impact technical operations or project deadlines.
    
    
    What Takeda can offer you:
    
    
    • 401(k) with company match and Annual Retirement Contribution Plan
      
    • Tuition reimbursement Company match of charitable contributions
      
    • Health & Wellness programs including onsite flu shots and health screenings
      
    • Generous time off for vacation and the option to purchase additional vacation days
      
    • Community Outreach Programs
      
      
      More about us:
      
      At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
      
      Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
      
      Base Salary Range: $101,500 to $145,000, based on candidate professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.
      
      In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
      
      #LI-SB1
      
      #LI-Onsite
      
      EEO Statement
      
      Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
      
      Locations
      
      San Diego, CA
      
      Worker Type
      
      Employee
      
      Worker Sub-Type
      
      Regular
      
      Time Type
      
      Full time

Keywords: Takeda, San Diego , Scientist I, GI Inflammation Discovery Research, Other , San Diego, California