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Computational Scientist, Multi-Omics

Location: San Diego
Posted on: February 9, 2024

Job Description:

Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
For more information, see our website at
Our Value
Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
We believe that diverse perspectives are foundational to scientific innovation and inquiry.
We are building a company where exceptional scientists and industry leaders from around the world work side by side to advance a shared mission.
Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives.
At Altos, we are all accountable for sustaining a diverse and inclusive environment.What You Will Contribute To Altos
Lab Description
The Kharchenko lab at Altos Labs San Diego Institute is studying how cells coordinate their activity within complex biological tissues, how these mechanisms break down in disease and injury, and the potential interventions that may improve tissue function. Much of the effort is focused on development and application of novel statistical methods and computational tools for understanding tissue function, including analysis of multi-omics and spatial assays.
Altos Labs aims to foster scientific creativity, providing research labs with both resources and freedom needed to pursue fundamental scientific challenges, including the ability of individual labs to publish and present their work for wider scientific community.
The Scientist or Senior Scientist in this position will be expected to lead the development and application of computational methods for analysis of single-cell multi-omics and spatial omics data, in the context of biological studies of different diseases, aging and other processes impacting tissue homeostasis. Emphasis will be placed on deciphering cell communications, control of proliferation within tissues, as well as epigenetic regulation of individual cells. Successful candidate will collaborate with both internal and external experimental groups, lead or participate in planning experimental designs, author and contribute to biological and methodological manuscripts, and contribute to seminars and other scientific initiations within Altos as well as a wider scientific community.
Who You Are

We are open to candidates with a range of experience, as the position can be filled at the Scientist I, Scientist II, or Senior Scientist level. The level of the position will depend on the qualifications of the selected candidate.
Minimum Qualifications

  • PhD in Computational Biology, Computer Science or a related discipline
  • A strong interest in conducting genomics research in a collaborative setting
  • Track record publications in peer-reviewed journals
  • Knowledge of statistical methods, probabilistic modeling techniques, and machine learning methods

    Preferred Qualifications

    • Track record of analysis of genomic data, including RNA, chromatin and DNA modifications, and proteins
    • Knowledge of single-cell analysis methods
    • Experience in developing tools in R or python, and experience with relevant repositories
    • Working knowledge of deep learning techniques, variational optimization, and generative models
    • Familiarity with multi-omics integration or spatial transcriptomics analysis

      The salary range forSan Diego:

      • Scientist I: $127,500 - $172,500
      • Scientist II: $150,000 - $228,800
      • Senior Scientist: $176,000 - $288,000

        Exact compensation may vary based on skills, experience, and location.
        For UK applicants, before submitting your application:
        - Please click here to read the Altos Labs EU and UK Applicant Privacy Notice ()
        - This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.What We Want You To Know
        We are a culture of collaboration and scientific freedom, and we believe in the values of diversity, inclusion and belonging to inspire innovation.
        Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
        This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
        Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).
        Thank you for your interest in Altos Labs where we strive for a culture of scientific freedom, learning, and belonging.
        Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at

Keywords: ALTOS LABS, San Diego , Computational Scientist, Multi-Omics, Other , San Diego, California

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