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Associate/Sr. Associate Process Development Upstream

Company: PaxVax, Inc.
Location: San Diego
Posted on: December 9, 2018

Job Description:

This is an incredible opportunity to join a small but growing clinical stage pharmaceutical company with a bright future. The Associate will be responsible for production of viral and viral like particle vaccines, including adherent and suspension cell culture in bioreactor, infection/transfection, purification and ultrafiltration/diafiltration processes. The successful candidate will be able to work in a fast-paced team oriented environment and be able to learn new skills quickly. This position will report directly to the Clinical Production Manager, Process Development and Production. Responsibilities: Perform adherent and suspension mammalian cell culture using disposable technologies Perform bioreactor operation and process development for mammalian suspension cells Perform viral or virus like particle purification by chromatography and ultrafiltration Perform lyophilization, encapsulation and capsule coating Author process development summary and tech reports Author manufacturing SOPs and batch records Design and execute studies to optimize viral and virus like particle vaccine production yeilds and stability Optimize mammalian cell culture and viral amplification in 10L to 200L bioreactor Lead and present projects within group as well as within the company Requirements: Bachelors of Science/engineering in Biology, Chemistry, Chemical Engineering, or related discipline Minimum of 1-5 years' relevant industry experience Team player and collaborator, ability to listen and communicate in a clear and timely manner Cell culture experience and strong aseptic technique cGMP experience Strong organizational and technical problem solving skills Demonstrated ability to think and act independently; accept supervision, work quickly and accurately in a fast-paced environment, critically analyze data and proactively solve problems Preferred Qualifications: Experience working with bioreactors, both rocker and/or stir tank Diafiltration/Ultrafiltration experience Travel: Potential 10%

Keywords: PaxVax, Inc., San Diego , Associate/Sr. Associate Process Development Upstream, Other , San Diego, California

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