Senior Scientist, Medicinal Chemistry
Location: Monrovia
Posted on: June 23, 2025
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Job Description:
Company Overview: Terray Therapeutics is a venture-backed
biotechnology company led by pioneers and long-time leaders in
artificial intelligence, synthetic chemistry, automation, and
nanotechnology. We’re generating chemical data purpose-built to
propel drug discovery into the information age — and we’re doing it
on a larger scale and faster than has ever before been possible.
Our closed loop system generates precise chemical datasets at
unrivaled scale that work seamlessly with AI to systematically map
biochemical interactions between small molecules and causes of
disease. Iterative cycles of virtual molecular design and
experimentation power AI and machine learning models, which in turn
guide the next cycle of design. With a chemistry engine that
measures billions of interactions daily and becomes increasingly
precise with every cycle, we can answer an unprecedented array of
questions — deriving insights that enable us to predictably create
drugs for patients in need. Position Summary: Terray is currently
seeking a motivated and creative synthetic chemist to join our
growing medicinal chemistry team. As an integral member of the
Preclinical Development department, the candidate will contribute
to hit-to-lead and lead optimization efforts across multiple
programs, leveraging our vast chemical datasets and proprietary
platforms to power state-of-the-art small molecule design and
synthesis. In this interdisciplinary role, the candidate will work
closely with teams from different functional areas in both
Preclinical Development and Computational and Data Science (CDS)
departments. The core responsibilities of this position are: Design
and synthesize bio-active molecules for programs in hit-to-lead
and/or lead optimization. Interpret large sets of potency, ADME and
DMPK data to uncover structure-activity relationships. Optimize the
properties for molecules across multiple series for in-vivo
exposure and efficacy. Work closely with Machine Learning and AI
teams to integrate predictive and generative modelling with
compound design. Manage and/or assist in managing external
chemistry efforts (CROs). Experience and Qualifications: Part of
Terray’s success is nurtured by a hands-on work environment where
everyone is accountable, vested in a vision of excellence, and
actively taking part in the success of the business. Terray
supports a positive work environment where employees can feel
engaged, recognized and empowered to be creative. Required
Qualifications: Ph.D. or postdoc in organic or synthetic chemistry
plus 2-5 years of experience in the biotech or pharmaceutical
industries OR Bachelor’s or Master’s degree in organic or synthetic
chemistry plus 10-15 years of experience in the biotech or
pharmaceutical industries Can demonstrate scientific initiative and
creativity in multi-step synthesis and/or reaction methodology
through primary authored peer-reviewed publications or patents.
Compensation Details: $150,000 - $219,000 (annually) depending on
experience; participation in the Company's option plan; 3%
retirement safe harbor contribution; fully-paid medical, dental,
vision, life and disability benefits.
Keywords: , San Diego , Senior Scientist, Medicinal Chemistry, Science, Research & Development , Monrovia, California
